Registering Capture B onto Capture A's tissue footprint
Spatial - Capture A
Spatial - Capture B
Final Tissue Masks
Generalized Procrustes Fit
Registers capture B's tissue footprint onto capture A's via shape matching — no
containment assumption, since two Visium captures are comparable in size rather than
one nesting inside the other (unlike the MEA→Spatial "snug" fit below).
Tissue Mask Pipeline
MEA
Spatial
Final Tissue Masks
Alignment Method
Grid-searches rotation, scale, and position for the transform where the Spatial capture area fits most snugly inside the MEA tissue mask. Press play to watch every candidate tried, in order, before it settles on the best fit.
0%
Drag the MEA outline onto the Spatial capture, then fine-tune with the sliders — starts from the snug-fit result above, so it's a nudge rather than starting from scratch.
STCapture Ahover · click to pin · scroll/drag on overlay
Time0–10 s
Lasso
Computing…
Draw Universe then
Local on the overlay to compare regions.
Local is auto-clipped to Universe.
Universe—
Local—
Local vs UniverseUnivLocal
A vs B—
Capture A vs Capture BCapture ACapture B
Zone A—
Zone B—
Zone A vs Zone BZone AZone B
Combined — MEA + Spatial overlay · scroll to zoom · drag to panSpatialMEA